Help them improve in areas of weakness
Encourage your children to be well-rounded
Academics are too important to neglect just because it does not come easy
Examples:
Women of Proverbs 31 - skills ranged from homemaking to business and management
David - shepherd, soldier, political leader, songwriter, and musician
Help them form upbuilding friendships
All young people need to belong to a group
If they are generally outsiders:
Teach your children to act differently - to not turn people off
Or steer them to toward another group
Don't be afraid to monitor your children's friendships
If you can't help someone be better or if either one of you makes the other a worse person, then you can not be friends